The U.S. Agency for International Development (USAID) Uzbekistan Education for Excellence Program, implemented by RTI International, conducted the Teaching and Learning Material (TLM) Uptake Study to inform immediate- and medium-term revisions to the TLMs developed by both the Program and the Ministry of Preschool and School Education (MoPSE). This desk review forms part of the TLM Uptake Study. Under the desk review, we evaluated the quality of the teacher guides (TGs) and student textbooks (STBs) developed for the Uzbek Language Arts (ULA) and Mathematics courses for grades 1–4 during the piloting of these materials in schools.