The Status of Instruction Study (SIS) aims to shed light on teachers’ knowledge, attitudes, beliefs, skills, and behaviors, as well as the available resources at the school level and for the targeted subjects, and how these resources are used. The SIS was designed to inform the customization and development of student textbooks, teacher guides, and teacher professional development approaches. This report presents the SIS methodology and findings from online surveys with over 4000 teachers, 183 school directors and 131 methodologists from all regions of Uzbekistan, including the Republic of Karakalpakstan and Tashkent City.