The Uzbekistan Education for Excellence Program (the Program), funded by the United States Agency for International Development, designed the Uzbek Language Arts (ULA) and Mathematics Teaching and Learning Material (TLM) Uptake Study to learn whether and how teachers and students in grades 2 and 4 are using the new teacher guides (TGs) and student textbooks (STBs). The Program used Phase 1 results and ensuing recommendations to inform the development and finalization of materials and ongoing teacher professional development (TPD) efforts. Phase 2 results served to determine whether teachers became more proficient over time in their application of the Student-Centered Strategies (SCSs) embedded in the TGs and STBs.