Since 2010, USAID has increased funding to partner country institutions by 50% [1], and the current administration’s localization agenda suggests that the government-to-government (G2G) modality may be increasingly frequent. Implementing partners operating in countries with a G2G arrangement, must pay careful attention to the meaning of technical assistance and system strengthening for scale and sustainability. This topic was covered by three presentations in a panel session, including: (1) Driving government ownership of a new language policy through a Government-to-Government partnership: The case of Senegal; (2) Government-to-Government programs to improve student learning: The case of Nepal; and (3) The case of Jordan