The Learning at Scale study aimed to investigate factors contributing to successful improvements in learning outcomes at scale in eight of the most effective large-scale education programs in LMICs (see the map of programs on the last page of this brief). These programs were selected based on their demonstrated gains in reading outcomes at-scale, from either midline or endline impact evaluations. The study addressed three overarching research questions, focused on understanding the components of instructional practices (Brief 1), instructional supports (Brief 2), and system supports (Brief 3) that lead to effective instruction. This brief focuses specifically on instructional practices. It addresses the following research question: What classroom ingredients (e.g., teaching practices, classroom environment) lead to learning in programs that are effective at scale?